InnateDB Protein
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IDBP-400924.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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Josd2
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Protein Name
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Josephin domain containing 2
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Synonyms
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1110007C05Rik;
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Species
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Mus musculus
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Ensembl Protein
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ENSMUSP00000113313
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InnateDB Gene
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IDBG-178791 (Josd2)
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Protein Structure
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Function |
Cleaves 'Lys-63'-linked poly-ubiquitin chains, and with lesser efficiency 'Lys-48'-linked poly-ubiquitin chains (in vitro). May act as a deubiquitinating enzyme (By similarity). {ECO:0000250}.
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Subcellular Localization |
Cytoplasm, cytosol {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
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Predicted by orthology |
Total |
6 [view]
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Molecular Function |
Accession |
GO Term |
GO:0004843
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ubiquitin-specific protease activity
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GO:0008242
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omega peptidase activity
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Biological Process |
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Cellular Component |
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PDB ID |
MGI:1913374
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InterPro |
IPR006155
Machado-Joseph disease protein MJD
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PFAM |
PF02099
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PRINTS |
PR01233
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9CR30
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PhosphoSite |
PhosphoSite-
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
66124
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UniGene |
Mm.358691
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RefSeq |
XP_006541134
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MGI ID |
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MGI Symbol |
Josd2
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OMIM |
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CCDS |
CCDS21208
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HPRD |
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IMGT |
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EMBL |
AK002872
AK003525
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GenPept |
BAB22420
BAB22837
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