Version 5.4
Mus musculus Protein: Cep97
Summary
InnateDB Protein IDBP-401031.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Cep97
Protein Name centrosomal protein 97
Synonyms 2810403B08Rik; 4932439K18Rik; AA437768; E130116N02Rik; Lrriq2;
Species Mus musculus
Ensembl Protein ENSMUSP00000112687
InnateDB Gene IDBG-166069 (Cep97)
Protein Structure
UniProt Annotation
Function Acts as a key negative regulator of ciliogenesis in collaboration with CCP110 by capping the mother centriole thereby preventing cilia formation. Required for recruitment of CCP110 to the centrosome (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 22 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 22 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0008150 biological_process
GO:0030030 cell projection organization
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0043234 protein complex
Protein Structure and Domains
PDB ID MGI:1921451
InterPro IPR000048 IQ motif, EF-hand binding site
IPR001611 Leucine-rich repeat
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00612
PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00015
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9CZ62
PhosphoSite PhosphoSite-Q9CZ62
TrEMBL
UniProt Splice Variant
Entrez Gene 74201
UniGene Mm.467086
RefSeq
MGI ID
MGI Symbol Cep97
OMIM
CCDS
HPRD
IMGT
EMBL AK012971 AK046486 AK154885 BC067049
GenPept AAH67049 BAB28575 BAC32752 BAE32902

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca