InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Ube2q2

Summary

InnateDB Protein

IDBP-401039.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Ube2q2

Protein Name

ubiquitin-conjugating enzyme E2Q (putative) 2

Synonyms

3010021M21Rik;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000112745

InnateDB Gene

IDBG-167643 (Ube2q2)

Protein Structure

UniProt Annotation

Function

Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys- 48'-linked polyubiquitination (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005524	ATP binding
GO:0016881	acid-amino acid ligase activity

Biological Process

GO:0070936

protein K48-linked ubiquitination

Cellular Component

GO:0005575	cellular_component
GO:0005737	cytoplasm

Protein Structure and Domains

PDB ID

MGI:2388672

InterPro

IPR000608 Ubiquitin-conjugating enzyme, E2
IPR016135 Ubiquitin-conjugating enzyme/RWD-like

PFAM

PF00179

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8K2Z8

PhosphoSite

PhosphoSite-Q8K2Z8

TrEMBL

UniProt Splice Variant

Entrez Gene

109161

UniGene

Mm.401695

RefSeq

XP_006510831

MGI ID

MGI Symbol

Ube2q2

OMIM

CCDS

HPRD

IMGT

EMBL

AK042515 AK076148 AK083216 AK150776 BC029111

GenPept

AAH29111 BAC36218 BAC38813 BAE20633 BAE29841