InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Traf3

Summary

InnateDB Protein

IDBP-401052.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Traf3

Protein Name

TNF receptor-associated factor 3

Synonyms

AI528849; amn; CAP-1; CD40bp; CRAF1; LAP1; T-BAM;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000112517

InnateDB Gene

IDBG-172558 (Traf3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 62 experimentally validated interaction(s) in this database.
They are also associated with 115 interaction(s) predicted by orthology.

Experimentally validated
Total	62 [view]
Protein-Protein	62 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	115 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004842	ubiquitin-protein transferase activity
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0031625	ubiquitin protein ligase binding
GO:0031996	thioesterase binding

Biological Process

GO:0001817	regulation of cytokine production
GO:0007165	signal transduction
GO:0008063	Toll signaling pathway
GO:0016567	protein ubiquitination
GO:0030162	regulation of proteolysis
GO:0032088	negative regulation of NF-kappaB transcription factor activity
GO:0033209	tumor necrosis factor-mediated signaling pathway
GO:0042981	regulation of apoptotic process
GO:0045087	innate immune response (InnateDB)
GO:0050688	regulation of defense response to virus