InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Cul5

Summary

InnateDB Protein

IDBP-401081.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Cul5

Protein Name

cullin 5

Synonyms

4921514I20Rik; 8430423K24Rik; AI852817; C030032G03Rik; C330021I08Rik; VACM-1; VACM1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113490

InnateDB Gene

IDBG-166023 (Cul5)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 18 experimentally validated interaction(s) in this database.
They are also associated with 335 interaction(s) predicted by orthology.

Experimentally validated
Total	18 [view]
Protein-Protein	18 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	335 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0031625	ubiquitin protein ligase binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0006511	ubiquitin-dependent protein catabolic process
GO:0006970	response to osmotic stress
GO:0051480	cytosolic calcium ion homeostasis

Cellular Component

GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005886	plasma membrane
GO:0031461	cullin-RING ubiquitin ligase complex
GO:0031466	Cul5-RING ubiquitin ligase complex

Protein Structure and Domains

PDB ID

MGI:1922967

InterPro

IPR001373 Cullin, N-terminal
IPR016158 Cullin homology
IPR016159 Cullin repeat-like-containing domain
IPR019559 Cullin protein, neddylation domain

PFAM

PF00888
PF10557

PRINTS

PIRSF

SMART

SM00182
SM00884

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q8BYN6

UniProt Splice Variant

Entrez Gene

75717

UniGene

Mm.482399

RefSeq

MGI ID

MGI Symbol

Cul5

OMIM

CCDS

HPRD

IMGT

EMBL

AC158384 AK038873

GenPept

BAC30157