Version 5.4
Mus musculus Protein: Slc12a8
Summary
InnateDB Protein IDBP-401237.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Slc12a8
Protein Name solute carrier family 12 (potassium/chloride transporters), member 8
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000113633
InnateDB Gene IDBG-155456 (Slc12a8)
Protein Structure
UniProt Annotation
Function Cation/chloride cotransporter that may play a role in the control of keratinocyte proliferation. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0015293 symporter activity
Biological Process
GO:0006810 transport
GO:0006813 potassium ion transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID MGI:2443672
InterPro IPR004841 Amino acid permease/ SLC12A domain
PFAM PF00324
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8VI23
PhosphoSite PhosphoSite-Q8VI23
TrEMBL
UniProt Splice Variant
Entrez Gene 171286
UniGene Mm.35253
RefSeq NP_001077371
MGI ID
MGI Symbol Slc12a8
OMIM
CCDS CCDS37317
HPRD
IMGT
EMBL AC121570 AC127412 AF319951 AK165080 BC030926
GenPept AAH30926 AAL37178 BAE38029

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca