Mus musculus Protein: Spock3 | |||||||||||
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Summary | |||||||||||
InnateDB Protein | IDBP-401245.4 | ||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||
Gene Symbol | Spock3 | ||||||||||
Protein Name | sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3 | ||||||||||
Synonyms | 2900045C01Rik; AI428471; mKIAA4039; | ||||||||||
Species | Mus musculus | ||||||||||
Ensembl Protein | ENSMUSP00000112930 | ||||||||||
InnateDB Gene | IDBG-157981 (Spock3) | ||||||||||
Protein Structure | |||||||||||
UniProt Annotation | |||||||||||
Function | May participate in diverse steps of neurogenesis. Inhibits the processing of pro-matrix metalloproteinase 2 (MMP-2) by MT1-MMP and MT3-MMP. May interfere with tumor invasion (By similarity). {ECO:0000250}. | ||||||||||
Subcellular Localization | Secreted, extracellular space, extracellular matrix {ECO:0000250}. | ||||||||||
Disease Associations | |||||||||||
Tissue Specificity | Expressed in brain. | ||||||||||
Comments | |||||||||||
Interactions | |||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
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Gene Ontology | |||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Protein Structure and Domains | |||||||||||
PDB ID | MGI:1920152 | ||||||||||
InterPro |
IPR000716
Thyroglobulin type-1 IPR002350 Kazal domain IPR019577 SPARC/Testican, calcium-binding domain |
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PFAM |
PF00086
PF00050 PF07648 PF10591 |
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PRINTS | |||||||||||
PIRSF | |||||||||||
SMART |
SM00211
SM00280 |
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TIGRFAMs | |||||||||||
Post-translational Modifications | |||||||||||
Modification | |||||||||||
Cross-References | |||||||||||
SwissProt | Q8BKV0 | ||||||||||
PhosphoSite | PhosphoSite-Q8BKV0 | ||||||||||
TrEMBL | Q571A9 | ||||||||||
UniProt Splice Variant | |||||||||||
Entrez Gene | 72902 | ||||||||||
UniGene | Mm.407128 | ||||||||||
RefSeq | NP_076178 | ||||||||||
MGI ID | |||||||||||
MGI Symbol | Spock3 | ||||||||||
OMIM | |||||||||||
CCDS | CCDS22326 | ||||||||||
HPRD | |||||||||||
IMGT | |||||||||||
EMBL | AJ278998 AK013644 AK049843 AK140736 AK220280 BC017601 BC053334 | ||||||||||
GenPept | AAH17601 AAH53334 BAB28935 BAC33951 BAD90205 BAE24460 CAC08506 | ||||||||||