Version 5.4
Mus musculus Protein: Foxred2
Summary
InnateDB Protein IDBP-401312.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Foxred2
Protein Name FAD-dependent oxidoreductase domain containing 2
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000113403
InnateDB Gene IDBG-158498 (Foxred2)
Protein Structure
UniProt Annotation
Function Probable flavoprotein which may function in endoplasmic reticulum associated degradation (ERAD). May bind non-native proteins in the endoplasmic reticulum and target them to the ubiquitination machinery for subsequent degradation (By similarity). {ECO:0000250}.
Subcellular Localization Endoplasmic reticulum lumen {ECO:0000255PROSITE-ProRule:PRU10138}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0016491 oxidoreductase activity
GO:0050660 flavin adenine dinucleotide binding
Biological Process
GO:0030433 ER-associated ubiquitin-dependent protein catabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005788 endoplasmic reticulum lumen
Protein Structure and Domains
PDB ID MGI:106315
InterPro IPR023753 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain
PFAM PF07992
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3USW5
PhosphoSite PhosphoSite-
TrEMBL Q3TBC9
UniProt Splice Variant
Entrez Gene 239554
UniGene Mm.391674
RefSeq NP_001161732
MGI ID
MGI Symbol Foxred2
OMIM
CCDS CCDS27607
HPRD
IMGT
EMBL AK140027 AK170795 AK171308 AL589650 BC086662 CH466545
GenPept AAH86662 BAE24215 BAE42033 BAE42384 CAP19080 EDL29655

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca