InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Rab3il1

Summary

InnateDB Protein

IDBP-401497.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Rab3il1

Protein Name

RAB3A interacting protein (rabin3)-like 1

Synonyms

1200014K04Rik; AI115013; C76746; Rab3ail1;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113828

InnateDB Gene

IDBG-142981 (Rab3il1)

Protein Structure

UniProt Annotation

Function

Guanine nucleotide exchange factor (GEF) which may activate RAB3A, a GTPase that regulates synaptic vesicle exocytosis. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. May also activates RAB8A and RAB8B (By similarity). {ECO:0000250}.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0017112	Rab guanyl-nucleotide exchange factor activity

Biological Process

GO:0015031	protein transport
GO:0032313	regulation of Rab GTPase activity

Cellular Component

GO:0005575

cellular_component

Protein Structure and Domains

PDB ID

MGI:1922010

InterPro

IPR009449 GDPGTP exchange factor Sec2p

PFAM

PF06428

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q8VDV3

PhosphoSite

PhosphoSite-Q8VDV3

TrEMBL

D3YZN2

UniProt Splice Variant

Entrez Gene

74760

UniGene

Mm.488681

RefSeq

XP_006527481

MGI ID

MGI Symbol

Rab3il1

OMIM

CCDS

HPRD

IMGT

EMBL

AC134437 AK132764 AK161298 BC020147

GenPept

AAH20147 BAE21345 BAE36305