InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Dhx34

Summary

InnateDB Protein

IDBP-401534.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Dhx34

Protein Name

DEAH (Asp-Glu-Ala-His) box polypeptide 34

Synonyms

1200013B07Rik; 1810012L18Rik; Ddx34; mKIAA0134;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113393

InnateDB Gene

IDBG-146174 (Dhx34)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.

Predicted by orthology
Total	6 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0004386	helicase activity
GO:0005524	ATP binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000956	nuclear-transcribed mRNA catabolic process
GO:0008152	metabolic process
GO:2000623	negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

Cellular Component

GO:0005575	cellular_component
GO:0016020	membrane

Protein Structure and Domains

PDB ID

MGI:1918973

InterPro

IPR001650 Helicase, C-terminal
IPR007502 Helicase-associated domain
IPR011545 DNA/RNA helicase, DEAD/DEAH box type, N-terminal
IPR011709 Domain of unknown function DUF1605
IPR014001 Helicase, superfamily 1/2, ATP-binding domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase

PFAM

PF00271
PF04408
PF00270
PF07717

PRINTS

PIRSF

SMART

SM00490
SM00847
SM00487

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite