Version 5.4
| Mus musculus Protein: Adam5 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-401542.4 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | Adam5 | ||||||||
| Protein Name | a disintegrin and metallopeptidase domain 5 | ||||||||
| Synonyms | tMDC II; tMDCII; | ||||||||
| Species | Mus musculus | ||||||||
| Ensembl Protein | ENSMUSP00000112422 | ||||||||
| InnateDB Gene | IDBG-142851 (Adam5) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | This is a non catalytic metalloprotease-like protein. May play a role in sperm-egg fusion (By similarity). {ECO:0000250}. | ||||||||
| Subcellular Localization | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Detected in brain, kidney, liver, lung, spleen and ovary. Highly expressed in testis. {ECO:0000269PubMed:7750654}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | MGI:104730 | ||||||||
| InterPro |
IPR000742
Epidermal growth factor-like domain IPR001590 Peptidase M12B, ADAM/reprolysin IPR001762 Blood coagulation inhibitor, Disintegrin IPR002870 Peptidase M12B, propeptide IPR006586 ADAM, cysteine-rich |
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| PFAM |
PF00008
PF01421 PF00200 PF01562 PF08516 |
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| PRINTS |
PR00289
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| PIRSF | |||||||||
| SMART |
SM00181
SM00050 SM00608 |
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| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q3TTE0 | ||||||||
| PhosphoSite | PhosphoSite- | ||||||||
| TrEMBL | |||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 11499 | ||||||||
| UniGene | Mm.143889 | ||||||||
| RefSeq | NP_031427 | ||||||||
| MGI ID | |||||||||
| MGI Symbol | Adam5 | ||||||||
| OMIM | |||||||||
| CCDS | CCDS52525 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AK016574 AK029519 AK161262 AK161415 AK161417 BC094237 U22059 | ||||||||
| GenPept | AAA74923 AAH94237 BAB30315 BAC26490 BAE36276 BAE36383 BAE36385 | ||||||||