Version 5.4
Mus musculus Protein: Klhl22
Summary
InnateDB Protein IDBP-401553.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Klhl22
Protein Name kelch-like 22 (Drosophila)
Synonyms
Species Mus musculus
Ensembl Protein ENSMUSP00000114115
InnateDB Gene IDBG-140145 (Klhl22)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Predicted by orthology
Total 20 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
Biological Process
GO:0000070 mitotic sister chromatid segregation
GO:0006513 protein monoubiquitination
GO:0007094 mitotic spindle assembly checkpoint
GO:0051301 cell division
Cellular Component
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005827 polar microtubule
GO:0031463 Cul3-RING ubiquitin ligase complex
GO:0072686 mitotic spindle
Protein Structure and Domains
PDB ID MGI:1337995
InterPro IPR000210 BTB/POZ-like
IPR006652 Kelch repeat type 1
IPR011333 BTB/POZ fold
IPR011498 Kelch repeat type 2
IPR011705 BTB/Kelch-associated
IPR013069 BTB/POZ
IPR017096 Kelch-like protein, gigaxonin type
PFAM PF01344
PF07646
PF07707
PF00651
PRINTS
PIRSF PIRSF037037
SMART SM00225
SM00612
SM00875
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H9KV05
UniProt Splice Variant
Entrez Gene 224023
UniGene Mm.282807
RefSeq
MGI ID
MGI Symbol Klhl22
OMIM
CCDS
HPRD
IMGT
EMBL AC087802
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca