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InnateDB Protein
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IDBP-4016.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SEC11C
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Protein Name
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SEC11 homolog C (S. cerevisiae)
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000299714
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InnateDB Gene
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IDBG-4014 (SEC11C)
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Protein Structure
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| Function |
Component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum. {ECO:0000250}.
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| Subcellular Localization |
Microsome membrane {ECO:0000250}; Single- pass type II membrane protein {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
| Experimentally validated |
| Total |
2
[view]
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| Protein-Protein |
1
[view]
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| Protein-DNA |
1
[view]
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| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| PDB ID |
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| InterPro |
IPR015927
Peptidase S24/S26A/S26B/S26C
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| PFAM |
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| PRINTS |
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-Q9BY50
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| TrEMBL |
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| UniProt Splice Variant |
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| Entrez Gene |
90701
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| UniGene |
Hs.690840
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| RefSeq |
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| HUGO |
HGNC:23400
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| OMIM |
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| CCDS |
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| HPRD |
15310
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| IMGT |
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| EMBL |
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| GenPept |
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Version 5.4