InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Gsta3

Summary

InnateDB Protein

IDBP-401634.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Gsta3

Protein Name

glutathione S-transferase, alpha 3

Synonyms

Gst2-3;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000113262

InnateDB Gene

IDBG-137022 (Gsta3)

Protein Structure

UniProt Annotation

Function

Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. This GST has a high catalytic activity for aflatoxin B1-8,9 epoxide.

Subcellular Localization

Cytoplasm.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	1 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004364	glutathione transferase activity
GO:0005515	protein binding

Biological Process

GO:0001657	ureteric bud development
GO:0006749	glutathione metabolic process

Cellular Component

GO:0005737

cytoplasm

Protein Structure and Domains

PDB ID

MGI:95856

InterPro

IPR003080 Glutathione S-transferase, alpha class
IPR004045 Glutathione S-transferase, N-terminal
IPR004046 Glutathione S-transferase, C-terminal
IPR010987 Glutathione S-transferase, C-terminal-like
IPR012336 Thioredoxin-like fold

PFAM