Version 5.4
Mus musculus Protein: Atf7ip2
Summary
InnateDB Protein IDBP-401698.4
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol Atf7ip2
Protein Name activating transcription factor 7 interacting protein 2
Synonyms 4930558K11Rik; BC018510; Get-1; PSM2;
Species Mus musculus
Ensembl Protein ENSMUSP00000113480
InnateDB Gene IDBG-132060 (Atf7ip2)
Protein Structure
UniProt Annotation
Function Recruiter that couples transcriptional factors to general transcription apparatus and thereby modulates transcription regulation and chromatin formation. Can both act as an activator or a repressor depending on the context. Mediates MBD1-dependent transcriptional repression, probably by recruiting complexes containing SETDB1. The complex formed with MBD1 and SETDB1 represses transcription and probably couples DNA methylation and histone H3 'Lys-9' trimethylation (H3K9me3) activity (By similarity). {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000250}.
Disease Associations
Tissue Specificity Expressed in testis. {ECO:0000269PubMed:16850184}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0008150 biological_process
Cellular Component
GO:0005730 nucleolus
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID MGI:1922579
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q3UL97
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 75329
UniGene Mm.108729
RefSeq NP_083529
MGI ID
MGI Symbol Atf7ip2
OMIM
CCDS CCDS49759
HPRD
IMGT
EMBL AK016180 AK077229 AK139862 AK145634 AY903215
GenPept AAX99226 BAB30138 BAC36698 BAE24164 BAE26553

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca