InnateDB: Systems Biology of the Innate Immune Response

Mus musculus Protein: Mmp12

Summary

InnateDB Protein

IDBP-401731.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

Mmp12

Protein Name

matrix metallopeptidase 12

Synonyms

AV378681; Mmel;

Species

Mus musculus

Ensembl Protein

ENSMUSP00000114129

InnateDB Gene

IDBG-132400 (Mmp12)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004222	metalloendopeptidase activity
GO:0005509	calcium ion binding
GO:0008237	metallopeptidase activity
GO:0008270	zinc ion binding

Biological Process

GO:0006508	proteolysis
GO:0042060	wound healing

Cellular Component

GO:0031012

extracellular matrix

Protein Structure and Domains

PDB ID

MGI:97005

InterPro

IPR000585 Hemopexin-like domain
IPR001818 Peptidase M10, metallopeptidase
IPR002477 Peptidoglycan binding-like
IPR006026 Peptidase, metallopeptidase
IPR016293 Peptidase M10A, stromelysin-type
IPR018487 Hemopexin-like repeats
IPR021190 Peptidase M10A

PFAM

PF00413
PF01471
PF00045

PRINTS

PR00138

PIRSF

PIRSF001191

SMART

SM00235
SM00120

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q6GX99

UniProt Splice Variant

Entrez Gene

17381

UniGene

Mm.488745

RefSeq

MGI ID

MGI Symbol

Mmp12

OMIM

CCDS

HPRD

IMGT

EMBL

AC169512 AK170500 AY622972

GenPept

AAT46403 BAE41839