InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GZMH

Summary

InnateDB Protein

IDBP-4022.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GZMH

Protein Name

granzyme H (cathepsin G-like 2, protein h-CCPX)

Synonyms

CCP-X; CGL-2; CSP-C; CTLA1; CTSGL2;

Species

Homo sapiens

Ensembl Protein

ENSP00000371988

InnateDB Gene

IDBG-4020 (GZMH)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0004252	serine-type endopeptidase activity

Biological Process

GO:0006508	proteolysis
GO:0006915	apoptotic process
GO:0019835	cytolysis

Cellular Component

GO:0016020	membrane
GO:0030141	secretory granule

Protein Structure and Domains

PDB ID

InterPro

IPR001254 Peptidase S1
IPR009003 Trypsin-like cysteine/serine peptidase domain

PFAM

PF00089

PRINTS

PIRSF

SMART

SM00020

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P20718

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

2999

UniGene

Hs.348264

RefSeq

NP_001257710

HUGO

HGNC:4710

OMIM

116831

CCDS

CCDS59243

HPRD

00290

IMGT

EMBL

AL136018 AY232657 AY232658 BC027974 CH471078 J02907 M36118 M57888 M72150

GenPept

AAA03248 AAA03514 AAA74885 AAA76859 AAH27974 AAP70247 AAP70248 EAW66004