InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ZNF85

Summary

InnateDB Protein

IDBP-40632.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ZNF85

Protein Name

zinc finger protein 85

Synonyms

HPF4; HTF1;

Species

Homo sapiens

Ensembl Protein

ENSP00000329793

InnateDB Gene

IDBG-40628 (ZNF85)

Protein Structure

UniProt Annotation

Function

May be a transcriptional repressor. {ECO:0000269PubMed:9839802}.

Subcellular Localization

Nucleus {ECO:0000269PubMed:9839802}.

Disease Associations

Tissue Specificity

Widely expressed, including in testis. {ECO:0000269PubMed:2023909, ECO:0000269PubMed:9839802}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	1 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003676	nucleic acid binding
GO:0003677	DNA binding
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0003714	transcription corepressor activity
GO:0046872	metal ion binding

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR001909 Krueppel-associated box
IPR007087 Zinc finger, C2H2
IPR015880 Zinc finger, C2H2-like

PFAM

PF01352
PF00096

PRINTS

PIRSF

SMART

SM00349
SM00355

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q03923

PhosphoSite

PhosphoSite-Q03923

TrEMBL

M0R385

UniProt Splice Variant

Entrez Gene

7639

UniGene

Hs.37138

RefSeq

NP_003420

HUGO

HGNC:13160

OMIM

603899

CCDS

CCDS32977

HPRD

04875

IMGT

EMBL

AC008739 BC068066 M61866 M61868 U35376

GenPept

AAA52689 AAA58671 AAA79179 AAH68066