Version 5.4
Homo sapiens Protein: CPLX4
Summary
InnateDB Protein IDBP-4070.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CPLX4
Protein Name complexin 4
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000299721
InnateDB Gene IDBG-4068 (CPLX4)
Protein Structure
UniProt Annotation
Function Positively regulates a late step in synaptic vesicle exocytosis. {ECO:0000250}.
Subcellular Localization Membrane; Lipid-anchor. Cell junction, synapse {ECO:0000250}. Note=Enriched at the synaptic terminal. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000149 SNARE binding
GO:0019905 syntaxin binding
Biological Process
GO:0006836 neurotransmitter transport
GO:0006887 exocytosis
GO:0046928 regulation of neurotransmitter secretion
Cellular Component
GO:0016020 membrane
GO:0030054 cell junction
GO:0045202 synapse
Protein Structure and Domains
PDB ID
InterPro IPR008849 Synaphin
PFAM PF05835
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q7Z7G2
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 339302
UniGene Hs.449884
RefSeq NP_857637
HUGO HGNC:24330
OMIM 609586
CCDS CCDS11973
HPRD 13091
IMGT
EMBL AB593158 AK123184 AY286502 BC106887 BC106888 BX640655 CH471096
GenPept AAI06888 AAI06889 AAP41128 BAC85549 BAJ84090 CAE45797 EAW63095

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca