Version 5.4
Homo sapiens Protein: ARSD
Summary
InnateDB Protein IDBP-41103.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARSD
Protein Name arylsulfatase D
Synonyms ASD;
Species Homo sapiens
Ensembl Protein ENSP00000370546
InnateDB Gene IDBG-41101 (ARSD)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Lysosome {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in the pancreas, kidney, liver, lung, placenta, brain and heart.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004065 arylsulfatase activity
GO:0008484 sulfuric ester hydrolase activity
GO:0046872 metal ion binding
Biological Process
GO:0006665 sphingolipid metabolic process
GO:0006687 glycosphingolipid metabolic process
GO:0008152 metabolic process
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005764 lysosome
GO:0005788 endoplasmic reticulum lumen
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000917 Sulfatase
IPR017850 Alkaline-phosphatase-like, core domain
PFAM PF00884
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P51689
PhosphoSite PhosphoSite-P51689
TrEMBL
UniProt Splice Variant
Entrez Gene 414
UniGene Hs.528631
RefSeq NP_001660
HUGO HGNC:717
OMIM 300002
CCDS CCDS35196
HPRD 02048
IMGT
EMBL AC005295 AF160499 BC020229 X83572
GenPept AAF22253 CAA58555

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca