Version 5.4
Homo sapiens Protein: FAM116A
Summary
InnateDB Protein IDBP-41391.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FAM116A
Protein Name family with sequence similarity 116, member A
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000311401
InnateDB Gene IDBG-41389 (FAM116A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0017112 Rab guanyl-nucleotide exchange factor activity
Biological Process
GO:0032851 positive regulation of Rab GTPase activity
GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin
Cellular Component
GO:0005737 cytoplasm
GO:0055037 recycling endosome
Protein Structure and Domains
PDB ID
InterPro IPR001194 DENN domain
IPR012860 Arf3-interacting protein 1, N-terminal domain
IPR018307 AVL9/DENND6 domain
PFAM PF02141
PF07792
PF09794
PRINTS
PIRSF
SMART SM00799
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8IWF6
PhosphoSite PhosphoSite-Q8IWF6
TrEMBL
UniProt Splice Variant
Entrez Gene 201627
UniGene Hs.91085
RefSeq NP_689891
HUGO HGNC:26635
OMIM
CCDS CCDS33773
HPRD 08756
IMGT
EMBL AC114480 AK074156 AK092288 BC040291 BC054343
GenPept AAH40291 AAH54343 BAB84982 BAC03852

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca