Version 5.4
Homo sapiens Protein: SLMAP
Summary
InnateDB Protein IDBP-41437.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLMAP
Protein Name sarcolemma associated protein
Synonyms SLAP;
Species Homo sapiens
Ensembl Protein ENSP00000373224
InnateDB Gene IDBG-41431 (SLMAP)
Protein Structure
UniProt Annotation
Function May play a role during myoblast fusion. {ECO:0000250}.
Subcellular Localization Cell membrane, sarcolemma {ECO:0000250}; Single-pass type IV membrane protein {ECO:0000250}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000250}. Note=Membrane-associated. Distributed in the transverse tubules and near the junctional sarcoplasmic reticulum. Detected along the Z- and M-lines in cardiomyocytes. Centrosome. Localizes to the centrosomes in a microtubule- dependent manner (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 60 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 60 [view]
Protein-Protein 60 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0006936 muscle contraction
Cellular Component
GO:0005790 smooth endoplasmic reticulum
GO:0005815 microtubule organizing center
GO:0005887 integral component of plasma membrane
GO:0042383 sarcolemma
Protein Structure and Domains
PDB ID
InterPro IPR000253 Forkhead-associated (FHA) domain
IPR008984 SMAD/FHA domain
PFAM PF00498
PRINTS
PIRSF
SMART SM00240
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q14BN4
PhosphoSite PhosphoSite-Q14BN4
TrEMBL
UniProt Splice Variant
Entrez Gene 7871
UniGene Hs.683435
RefSeq XP_005265514
HUGO HGNC:16643
OMIM 602701
CCDS
HPRD 04079
IMGT
EMBL AB046821 AF100750 AF304450 AK124200 AL834538 AY358410 BC114627 BC115701 CR627321
GenPept AAD43014 AAG41949 AAI14628 AAI15702 AAQ88776 BAB13427 BAC85803 CAD39194 CAH10369

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca