InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PRIM1

Summary

InnateDB Protein

IDBP-41540.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PRIM1

Protein Name

primase, DNA, polypeptide 1 (49kDa)

Synonyms

p49;

Species

Homo sapiens

Ensembl Protein

ENSP00000350491

InnateDB Gene

IDBG-41538 (PRIM1)

Protein Structure

UniProt Annotation

Function

DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	19 [view]
Protein-Protein	19 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003896	DNA primase activity
GO:0005515	protein binding
GO:0046872	metal ion binding

Biological Process

GO:0000082	G1/S transition of mitotic cell cycle
GO:0000278	mitotic cell cycle
GO:0000722	telomere maintenance via recombination
GO:0000723	telomere maintenance
GO:0006269	DNA replication, synthesis of RNA primer
GO:0006270	DNA replication initiation
GO:0006271	DNA strand elongation involved in DNA replication
GO:0032201	telomere maintenance via semi-conservative replication