Version 5.4
Homo sapiens Protein: SLITRK5
Summary
InnateDB Protein IDBP-41586.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLITRK5
Protein Name SLIT and NTRK-like family, member 5
Synonyms bA364G4.2; LRRC11;
Species Homo sapiens
Ensembl Protein ENSP00000366283
InnateDB Gene IDBG-41584 (SLITRK5)
Protein Structure
UniProt Annotation
Function Suppresses neurite outgrowth. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed predominantly in the cerebral cortex of the brain but also at low levels in the spinal cord and medulla. {ECO:0000269PubMed:14557068}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 0
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007268 synaptic transmission
GO:0007409 axonogenesis
GO:0007625 grooming behavior
GO:0009410 response to xenobiotic stimulus
GO:0021756 striatum development
GO:0030534 adult behavior
GO:0043588 skin development
GO:0048813 dendrite morphogenesis
GO:0072358 cardiovascular system development
Cellular Component
GO:0016021 integral component of membrane
GO:0043235 receptor complex
Protein Structure and Domains
PDB ID
InterPro IPR000483 Cysteine-rich flanking region, C-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
PFAM PF01463
PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00082
SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O94991
PhosphoSite PhosphoSite-O94991
TrEMBL
UniProt Splice Variant
Entrez Gene 26050
UniGene Hs.604914
RefSeq NP_056382
HUGO HGNC:20295
OMIM 609680
CCDS CCDS9465
HPRD 18065
IMGT
EMBL AB020725 AK024251 AL603883 BC098106 BC103509 CH471085
GenPept AAH98106 AAI03510 BAA74941 BAG51280 CAH73026 EAX08917

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca