Version 5.4
Homo sapiens Protein: MAP9
Summary
InnateDB Protein IDBP-42327.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAP9
Protein Name microtubule-associated protein 9
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000310593
InnateDB Gene IDBG-42325 (MAP9)
Protein Structure
UniProt Annotation
Function Involved in organization of the bipolar mitotic spindle. Required for bipolar spindle assembly, mitosis progression and cytokinesis. May act by stabilizing interphase microtubules. {ECO:0000269PubMed:16049101}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:16049101}. Cytoplasm, cytoskeleton {ECO:0000269PubMed:16049101}. Cytoplasm, cytoskeleton, spindle {ECO:0000269PubMed:16049101}. Note=Localizes to microtubules in interphase, associates with the mitotic spindle during mitosis, localizes to the central body during cytokinesis.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0000910 cytokinesis
GO:0007067 mitotic nuclear division
GO:0007088 regulation of mitosis
GO:0051225 spindle assembly
GO:0090307 spindle assembly involved in mitosis
Cellular Component
GO:0000235 astral microtubule
GO:0005737 cytoplasm
GO:0005818 aster
GO:0005819 spindle
GO:0005874 microtubule
GO:0015630 microtubule cytoskeleton
GO:0072686 mitotic spindle
GO:1990023 mitotic spindle midzone
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q49MG5
PhosphoSite PhosphoSite-Q49MG5
TrEMBL C9JXH8
UniProt Splice Variant
Entrez Gene 79884
UniGene Hs.633520
RefSeq NP_001034669
HUGO HGNC:26118
OMIM 610070
CCDS CCDS35493
HPRD 07957
IMGT
EMBL AC097467 AK024730 AK024812 AY690636 BC128541 CR749274
GenPept AAI28542 AAW02921 AAY40981 BAB14978 BAB15017 CAH18129

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca