Version 5.4
Homo sapiens Protein: CTRB1
Summary
InnateDB Protein IDBP-42452.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CTRB1
Protein Name chymotrypsinogen B1
Synonyms CTRB;
Species Homo sapiens
Ensembl Protein ENSP00000354294
InnateDB Gene IDBG-42450 (CTRB1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Secreted, extracellular space.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis
GO:0006766 vitamin metabolic process
GO:0006767 water-soluble vitamin metabolic process
GO:0007586 digestion
GO:0009235 cobalamin metabolic process
GO:0022617 extracellular matrix disassembly
GO:0030198 extracellular matrix organization
GO:0044281 small molecule metabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro IPR001254 Peptidase S1
IPR001314 Peptidase S1A, chymotrypsin-type
IPR009003 Trypsin-like cysteine/serine peptidase domain
PFAM PF00089
PRINTS PR00722
PIRSF
SMART SM00020
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P17538
PhosphoSite PhosphoSite-P17538
TrEMBL
UniProt Splice Variant
Entrez Gene 1504
UniGene
RefSeq NP_001897
HUGO HGNC:2521
OMIM 118890
CCDS CCDS32490
HPRD 00345
IMGT
EMBL BC005385 BT007356 M24400
GenPept AAA52128 AAH05385 AAP36020

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca