InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: STRA8

Summary

InnateDB Protein

IDBP-42568.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

STRA8

Protein Name

stimulated by retinoic acid gene 8 homolog (mouse)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000275764

InnateDB Gene

IDBG-42566 (STRA8)

Protein Structure

UniProt Annotation

Function

Meiosis-inducer required for the transition into meiosis for both female and male germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase (By similarity). {ECO:0000250}.

Subcellular Localization

Cytoplasm {ECO:0000250UniProtKB:P70278}.

Disease Associations

Tissue Specificity

Expressed specifically in testis. {ECO:0000269PubMed:12489526}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
They are also associated with 5 interaction(s) predicted by orthology.

Predicted by orthology
Total	5 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0046983	protein dimerization activity

Biological Process

GO:0001541	ovarian follicle development
GO:0006260	DNA replication
GO:0007066	female meiosis sister chromatid cohesion
GO:0007129	synapsis
GO:0007131	reciprocal meiotic recombination
GO:0007283	spermatogenesis
GO:0009566	fertilization
GO:0010032	meiotic chromosome condensation
GO:0033315	meiotic DNA replication checkpoint
GO:0042138	meiotic DNA double-strand break formation
GO:0046620	regulation of organ growth
GO:0048599	oocyte development
GO:0071300	cellular response to retinoic acid