InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NUP205

Summary

InnateDB Protein

IDBP-42712.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NUP205

Protein Name

nucleoporin 205kDa

Synonyms

C7orf14;

Species

Homo sapiens

Ensembl Protein

ENSP00000285968

InnateDB Gene

IDBG-42710 (NUP205)

Protein Structure

UniProt Annotation

Function

Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance. May anchor NUP62 and other nucleoporins, but not NUP153 and TPR, to the NPC. {ECO:0000269PubMed:15229283}.

Subcellular Localization

Nucleus membrane; Peripheral membrane protein. Nucleus, nuclear pore complex. Note=Localized near the center, on both the cytoplasmic and nuclear side, of the NPC core structure.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 31 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	31 [view]
Protein-Protein	31 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0017056	structural constituent of nuclear pore

Biological Process

GO:0000059	protein import into nucleus, docking
GO:0000278	mitotic cell cycle
GO:0005975	carbohydrate metabolic process
GO:0006913	nucleocytoplasmic transport
GO:0007077	mitotic nuclear envelope disassembly
GO:0008645	hexose transport
GO:0010827	regulation of glucose transport
GO:0015758	glucose transport
GO:0016032	viral process
GO:0019221	cytokine-mediated signaling pathway
GO:0044281	small molecule metabolic process
GO:0051028	mRNA transport
GO:0051292	nuclear pore complex assembly
GO:0055085	transmembrane transport