Version 5.4
Homo sapiens Protein: KCTD15
Summary
InnateDB Protein IDBP-42759.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCTD15
Protein Name potassium channel tetramerisation domain containing 15
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000284006
InnateDB Gene IDBG-42757 (KCTD15)
Protein Structure
UniProt Annotation
Function During embryonic development, interferes with neural crest formation (By similarity). Inhibits AP2 transcriptional activity by interaction with its activation domain. {ECO:0000250, ECO:0000269PubMed:23382213}.
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007275 multicellular organismal development
GO:0051260 protein homooligomerization
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000210 BTB/POZ-like
IPR003131 Potassium channel tetramerisation-type BTB domain
IPR011333 BTB/POZ fold
PFAM PF02214
PRINTS
PIRSF
SMART SM00225
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q96SI1
PhosphoSite PhosphoSite-Q96SI1
TrEMBL K7EQS3
UniProt Splice Variant
Entrez Gene 79047
UniGene Hs.609610
RefSeq NP_076981
HUGO HGNC:23297
OMIM 615240
CCDS CCDS12434
HPRD 13765
IMGT
EMBL AC005615 AC008556 AK027901 AK291465 BC001185 BC009335
GenPept AAH01185 AAH09335 BAB55443 BAF84154

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca