Version 5.4
| Homo sapiens Protein: SLC13A4 | |||||||||
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| Summary | |||||||||
| InnateDB Protein | IDBP-42799.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | SLC13A4 | ||||||||
| Protein Name | solute carrier family 13 (sodium/sulfate symporters), member 4 | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Protein | ENSP00000297282 | ||||||||
| InnateDB Gene | IDBG-42795 (SLC13A4) | ||||||||
| Protein Structure |
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| UniProt Annotation | |||||||||
| Function | Sodium/sulfate cotransporter that mediates sulfate reabsorption in the high endothelial venules (HEV). {ECO:0000269PubMed:10535998, ECO:0000269PubMed:15607730}. | ||||||||
| Subcellular Localization | Membrane; Multi-pass membrane protein. | ||||||||
| Disease Associations | |||||||||
| Tissue Specificity | Highly expressed in placenta and testis with intermediate levels in brain and lower levels in heart, thymus and liver. {ECO:0000269PubMed:10535998, ECO:0000269PubMed:15607730}. | ||||||||
| Comments | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Protein Structure and Domains | |||||||||
| PDB ID | |||||||||
| InterPro |
IPR001898
Sodium/sulphate symporter IPR004680 Citrate transporter-like domain IPR010656 TRAP C4-dicarboxylate transport system permease DctM subunit |
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| PFAM |
PF00939
PF03600 PF06808 |
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| PRINTS | |||||||||
| PIRSF | |||||||||
| SMART | |||||||||
| TIGRFAMs | |||||||||
| Post-translational Modifications | |||||||||
| Modification | |||||||||
| Cross-References | |||||||||
| SwissProt | Q9UKG4 | ||||||||
| PhosphoSite | PhosphoSite-Q9UKG4 | ||||||||
| TrEMBL | V9GZ66 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 26266 | ||||||||
| UniGene | Hs.713463 | ||||||||
| RefSeq | NP_036582 | ||||||||
| HUGO | HGNC:15827 | ||||||||
| OMIM | 604309 | ||||||||
| CCDS | CCDS5840 | ||||||||
| HPRD | 10372 | ||||||||
| IMGT | |||||||||
| EMBL | AC091736 AF169301 BC030689 CH236950 CH471070 | ||||||||
| GenPept | AAF05907 AAH30689 EAL24058 EAW83858 | ||||||||