InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CLCN4

Summary

InnateDB Protein

IDBP-42909.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CLCN4

Protein Name

chloride channel 4

Synonyms

ClC-4; ClC-4A; CLC4;

Species

Homo sapiens

Ensembl Protein

ENSP00000370209

InnateDB Gene

IDBG-42905 (CLCN4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005247	voltage-gated chloride channel activity
GO:0030554	adenyl nucleotide binding

Biological Process

GO:0006821	chloride transport
GO:0034220	ion transmembrane transport
GO:0044070	regulation of anion transport
GO:0055085	transmembrane transport

Cellular Component

GO:0016020	membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000644 CBS domain
IPR001807 Chloride channel, voltage gated
IPR002246 Chloride channel ClC-4
IPR014743 Chloride channel, core

PFAM

PF00571
PF00654

PRINTS

PR00762
PR01115

PIRSF

SMART

SM00116

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q75N13

UniProt Splice Variant

Entrez Gene

1183

UniGene

Hs.495674

RefSeq

HUGO

HGNC:2022

OMIM

302910

CCDS

HPRD

02362

IMGT

EMBL

AC002364 AC003666 AC121345 CH471074

GenPept

AAC83175 EAW98777