InnateDB Protein
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IDBP-43613.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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NDUFS3
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Protein Name
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NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase)
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Synonyms
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CI-30;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000263774
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InnateDB Gene
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IDBG-239864 (NDUFS3)
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Protein Structure
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Function |
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). {ECO:0000250}.
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Subcellular Localization |
Mitochondrion inner membrane.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 38 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
38
[view]
|
Protein-Protein |
36
[view]
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Protein-DNA |
2
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR001268
NADH:ubiquinone oxidoreductase, 30kDa subunit
IPR010218
NADH dehydrogenase, subunit C
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PFAM |
PF00329
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
O75489
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PhosphoSite |
PhosphoSite-O75489
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TrEMBL |
Q9UF24
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UniProt Splice Variant |
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Entrez Gene |
4722
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UniGene |
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RefSeq |
NP_004542
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HUGO |
HGNC:7710
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OMIM |
603846
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CCDS |
CCDS7941
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HPRD |
10355
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IMGT |
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EMBL |
AF067139
AF100743
AF200954
AK313802
AL135819
BC000617
CH471064
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GenPept |
AAC27451
AAD40386
AAG17541
AAH00617
BAG36538
CAB63881
EAW67895
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