InnateDB Protein
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IDBP-44612.5
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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TAS2R5
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Protein Name
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taste receptor, type 2, member 5
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000247883
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InnateDB Gene
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IDBG-44610 (TAS2R5)
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Protein Structure
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Function |
Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5.
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Subcellular Localization |
Membrane; Multi-pass membrane protein.
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Disease Associations |
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Tissue Specificity |
Expressed in subsets of taste receptor cells of the tongue and palate epithelium and exclusively in gustducin- positive cells.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR007960
Mammalian taste receptor
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PFAM |
PF05296
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9NYW4
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PhosphoSite |
PhosphoSite-Q9NYW4
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TrEMBL |
Q50KW4
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UniProt Splice Variant |
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Entrez Gene |
54429
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UniGene |
Hs.675370
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RefSeq |
NP_061853
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HUGO |
HGNC:14912
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OMIM |
605062
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CCDS |
CCDS5869
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HPRD |
05453
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IMGT |
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EMBL |
AB199028
AB199029
AC004979
AF227132
AY724966
BC069509
BC101586
BC101588
CH236950
CH471070
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GenPept |
AAF43905
AAH69509
AAI01587
AAI01589
AAS02040
AAU21159
BAD97933
BAD97934
EAL24015
EAW83984
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