Version 5.4
Homo sapiens Protein: GXYLT2
Summary
InnateDB Protein IDBP-44929.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GXYLT2
Protein Name glucoside xylosyltransferase 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000374268
InnateDB Gene IDBG-44927 (GXYLT2)
Protein Structure
UniProt Annotation
Function Glycosyltransferase which elongates the O-linked glucose attached to EGF-like repeats in the extracellular domain of Notch proteins by catalyzing the addition of xylose. {ECO:0000269PubMed:19940119}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type II membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0016757 transferase activity, transferring glycosyl groups
GO:0035252 UDP-xylosyltransferase activity
Biological Process
GO:0016266 O-glycan processing
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002495 Glycosyl transferase, family 8
IPR029044 Nucleotide-diphospho-sugar transferases
PFAM PF01501
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A0PJZ3
PhosphoSite PhosphoSite-A0PJZ3
TrEMBL C9J3Q6
UniProt Splice Variant
Entrez Gene 727936
UniGene Hs.710275
RefSeq NP_001073862
HUGO HGNC:33383
OMIM 613322
CCDS CCDS46870
HPRD
IMGT
EMBL AC098481 AC114876 BC127733
GenPept AAI27734

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

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Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca