InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: IDI2

Summary

InnateDB Protein

IDBP-44972.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IDI2

Protein Name

isopentenyl-diphosphate delta isomerase 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000277517

InnateDB Gene

IDBG-44970 (IDI2)

Protein Structure

UniProt Annotation

Function

Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). {ECO:0000269PubMed:17202134}.

Subcellular Localization

Peroxisome {ECO:0000269PubMed:17202134}.

Disease Associations

Tissue Specificity

Detected in skeletal muscle. {ECO:0000269PubMed:17202134}.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.

Experimentally validated
Total	2 [view]
Protein-Protein	2 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004452	isopentenyl-diphosphate delta-isomerase activity
GO:0016787	hydrolase activity
GO:0046872	metal ion binding

Biological Process

GO:0006695	cholesterol biosynthetic process
GO:0008299	isoprenoid biosynthetic process
GO:0044281	small molecule metabolic process
GO:0046490	isopentenyl diphosphate metabolic process
GO:0050992	dimethylallyl diphosphate biosynthetic process