Version 5.4
Homo sapiens Protein: IGFLR1
Summary
InnateDB Protein IDBP-45098.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IGFLR1
Protein Name IGF-like family receptor 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000246532
InnateDB Gene IDBG-45096 (IGFLR1)
Protein Structure
UniProt Annotation
Function Probable cell membrane receptor for the IGF-like family proteins. Binds IGFL1 and IGFL3 with a higher affinity. May also bind IGFL2. {ECO:0000269PubMed:21454693}.
Subcellular Localization Cell membrane {ECO:0000269PubMed:21454693}; Single-pass type I membrane protein {ECO:0000269PubMed:21454693}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005886 plasma membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR011029 Death-like domain
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9H665
PhosphoSite PhosphoSite-Q9H665
TrEMBL K7ESC2
UniProt Splice Variant
Entrez Gene 79713
UniGene Hs.352548
RefSeq
HUGO HGNC:23620
OMIM 614143
CCDS CCDS12472
HPRD 07996
IMGT
EMBL AD000671 AK026226 BC031329 BC126481 BC126483
GenPept AAH31329 AAI26482 AAI26484 BAB15400

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca