Version 5.4
Homo sapiens Protein: PPP1R1B
Summary
InnateDB Protein IDBP-45761.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP1R1B
Protein Name protein phosphatase 1, regulatory (inhibitor) subunit 1B
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000254079
InnateDB Gene IDBG-45759 (PPP1R1B)
Protein Structure
UniProt Annotation
Function Inhibitor of protein-phosphatase 1.
Subcellular Localization Cytoplasm.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004860 protein kinase inhibitor activity
GO:0004864 protein phosphatase inhibitor activity
GO:0008599 protein phosphatase type 1 regulator activity
GO:0031748 D1 dopamine receptor binding
GO:0031749 D2 dopamine receptor binding
GO:0031750 D3 dopamine receptor binding
GO:0031751 D4 dopamine receptor binding
GO:0031752 D5 dopamine receptor binding
Biological Process
GO:0001975 response to amphetamine
GO:0006351 transcription, DNA-templated
GO:0006469 negative regulation of protein kinase activity
GO:0007165 signal transduction
GO:0007621 negative regulation of female receptivity
GO:0008542 visual learning
GO:0035556 intracellular signal transduction
GO:0043086 negative regulation of catalytic activity
GO:0050790 regulation of catalytic activity
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol
GO:0043025 neuronal cell body
Protein Structure and Domains
PDB ID
InterPro IPR008466 Protein phosphatase inhibitor, 1DARPP-32
PFAM PF05395
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UD71
PhosphoSite PhosphoSite-Q9UD71
TrEMBL Q9NNW1
UniProt Splice Variant
Entrez Gene 84152
UniGene Hs.286192
RefSeq NP_115568
HUGO HGNC:9287
OMIM 604399
CCDS CCDS11339
HPRD 05097
IMGT
EMBL AF233349 AF435972 AF435973 AF435974 AF435975 AF464196 AK024593 AK123112 AK127542 AY070271 BC001519 BT007076 CH471152
GenPept AAF43435 AAH01519 AAL59016 AAM76683 AAP35094 AAP35095 AAP35096 AAP35097 AAP35098 AAP35739 BAB14931 BAG53871 BAG54520 EAW60580 EAW60581 EAW60582 EAW60583

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca