InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HNRNPA0

Summary

InnateDB Protein

IDBP-46209.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HNRNPA0

Protein Name

heterogeneous nuclear ribonucleoprotein A0

Synonyms

HNRPA0;

Species

Homo sapiens

Ensembl Protein

ENSP00000316042

InnateDB Gene

IDBG-46207 (HNRNPA0)

Protein Structure

UniProt Annotation

Function

mRNA-binding component of ribonucleosomes. Specifically binds AU-rich element (ARE)-containing mRNAs. Involved in post- transcriptional regulation of cytokines mRNAs. {ECO:0000269PubMed:12456657}.

Subcellular Localization

Nucleus {ECO:0000250}. Note=Component of ribonucleosomes. {ECO:0000250}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 103 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	103 [view]
Protein-Protein	100 [view]
Protein-DNA	1 [view]
Protein-RNA	2 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000166	nucleotide binding
GO:0003676	nucleic acid binding
GO:0003723	RNA binding
GO:0017091	AU-rich element binding
GO:0019901	protein kinase binding
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000398	mRNA splicing, via spliceosome
GO:0006397	mRNA processing
GO:0006954	inflammatory response
GO:0008380	RNA splicing
GO:0010467	gene expression
GO:0032496	response to lipopolysaccharide
GO:0070935	3'-UTR-mediated mRNA stabilization