Homo sapiens Protein: TPK1
Summary
InnateDB Protein IDBP-46680.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TPK1
Protein Name thiamin pyrophosphokinase 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000367339
InnateDB Gene IDBG-46676 (TPK1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004788 thiamine diphosphokinase activity
GO:0005524 ATP binding
GO:0030975 thiamine binding
Biological Process
GO:0009229 thiamine diphosphate biosynthetic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR007371 Thiamin pyrophosphokinase, catalytic domain
IPR007373 Thiamin pyrophosphokinase, vitamin B1-binding domain
IPR016966 Thiamin pyrophosphokinase, eukaryotic
PFAM PF04263
PF04265
PRINTS
PIRSF PIRSF031057
SMART SM00983
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL F5GZG6
UniProt Splice Variant
Entrez Gene 27010
UniGene Hs.660232
RefSeq NP_001035947
HUGO HGNC:17358
OMIM 606370
CCDS CCDS55178
HPRD 06967
IMGT
EMBL AC004534 AC004743 AC004833 AC004864 AC005677 AC074384
GenPept