Version 5.4
Homo sapiens Protein: SERPING1
Summary
InnateDB Protein IDBP-46859.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SERPING1
Protein Name serpin peptidase inhibitor, clade G (C1 inhibitor), member 1
Synonyms C1IN; C1INH; C1NH; HAE1; HAE2;
Species Homo sapiens
Ensembl Protein ENSP00000367574
InnateDB Gene IDBG-46853 (SERPING1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 14 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0008233 peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0010951 negative regulation of endopeptidase activity
GO:0030193 regulation of blood coagulation
GO:0045087 innate immune response (InnateDB)
GO:0045916 negative regulation of complement activation
Cellular Component
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro IPR023796 Serpin domain
PFAM PF00079
PRINTS
PIRSF
SMART SM00093
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL B4E1H2
UniProt Splice Variant
Entrez Gene 710
UniGene Hs.706637
RefSeq
HUGO HGNC:1228
OMIM 606860
CCDS
HPRD 06033
IMGT
EMBL AK303809 AK303840 AP000662 AP002893
GenPept BAG64762 BAG64784

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca