Version 5.4
Homo sapiens Protein: TMX2
Summary
InnateDB Protein IDBP-47091.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMX2
Protein Name thioredoxin-related transmembrane protein 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000367562
InnateDB Gene IDBG-240260 (TMX2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Widely expressed. {ECO:0000269PubMed:12670024}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 12 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
Biological Process
GO:0008150 biological_process
GO:0045454 cell redox homeostasis
Cellular Component
GO:0005575 cellular_component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR012336 Thioredoxin-like fold
IPR013766 Thioredoxin domain
PFAM PF13098
PF13192
PF13462
PF13905
PF00085
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y320
PhosphoSite PhosphoSite-Q9Y320
TrEMBL
UniProt Splice Variant
Entrez Gene 51075
UniGene Hs.654965
RefSeq NP_001137484
HUGO HGNC:30739
OMIM
CCDS CCDS44601
HPRD
IMGT
EMBL AF059753 AF132965 AK075359 AK223058 AK297688 AY358501 AY451237 BC000666 BC093062
GenPept AAD27740 AAG43122 AAH00666 AAH93062 AAQ88865 AAS66642 BAC11569 BAD96778 BAH12650

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca