Version 5.4
Homo sapiens Protein: ENPP1
Summary
InnateDB Protein IDBP-473584.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ENPP1
Protein Name ectonucleotide pyrophosphatase/phosphodiesterase 1
Synonyms ARHR2; COLED; M6S1; NPP1; NPPS; PC-1; PCA1; PDNP1;
Species Homo sapiens
Ensembl Protein ENSP00000422424
InnateDB Gene IDBG-96591 (ENPP1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0005044 scavenger receptor activity
GO:0030247 polysaccharide binding
Biological Process
GO:0006898 receptor-mediated endocytosis
GO:0006955 immune response
GO:0008152 metabolic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001212 Somatomedin B domain
IPR002591 Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase
IPR017850 Alkaline-phosphatase-like, core domain
IPR020436 Somatomedin B, chordata
PFAM PF01033
PF01663
PRINTS PR00022
PIRSF
SMART SM00201
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9NS95
UniProt Splice Variant
Entrez Gene 5167
UniGene Hs.671580
RefSeq
HUGO HGNC:3356
OMIM 173335
CCDS
HPRD 01415
IMGT
EMBL AB032016 AL117378 AL139805
GenPept BAA97562

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca