InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CSF1R

Summary

InnateDB Protein

IDBP-473684.3

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CSF1R

Protein Name

colony stimulating factor 1 receptor

Synonyms

C-FMS; CD115; CSF-1R; CSFR; FIM2; FMS; HDLS; M-CSF-R;

Species

Homo sapiens

Ensembl Protein

ENSP00000422212

InnateDB Gene

IDBG-53268 (CSF1R)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 44 experimentally validated interaction(s) in this database.
They are also associated with 19 interaction(s) predicted by orthology.

Experimentally validated
Total	44 [view]
Protein-Protein	35 [view]
Protein-DNA	9 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	19 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004672	protein kinase activity
GO:0004714	transmembrane receptor protein tyrosine kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468	protein phosphorylation
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
GO:0018108	peptidyl-tyrosine phosphorylation

Cellular Component

GO:0016020

membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000719 Protein kinase domain
IPR001245 Serine-threonine/tyrosine-protein kinase catalytic domain
IPR003598 Immunoglobulin subtype 2
IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
IPR011009 Protein kinase-like domain
IPR013151 Immunoglobulin

PFAM

PF00069
PF07714
PF00047

PRINTS

PR00109

PIRSF

SMART

SM00408
SM00409

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt