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InnateDB Protein
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IDBP-473815.3
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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PIK3R1
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Protein Name
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phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
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Synonyms
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AGM7; GRB1; IMD36; p85; p85-ALPHA;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000429766
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InnateDB Gene
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IDBG-25037 (PIK3R1)
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Protein Structure
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| Function |
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| Subcellular Localization |
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 274 experimentally validated interaction(s) in this database.
They are also associated with 57 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
274
[view]
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| Protein-Protein |
273
[view]
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| Protein-DNA |
0
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| Protein-RNA |
0
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| DNA-DNA |
1
[view]
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
57 [view]
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Molecular Function |
| Accession |
GO Term |
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GO:0035014
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phosphatidylinositol 3-kinase regulator activity
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| Biological Process |
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GO:0043551
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regulation of phosphatidylinositol 3-kinase activity
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GO:0045087
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innate immune response (InnateDB)
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR000980
SH2 domain
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| PFAM |
PF00017
PF14633
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| PRINTS |
PR00401
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| PIRSF |
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| SMART |
SM00252
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| TIGRFAMs |
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| Modification |
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| SwissProt |
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| PhosphoSite |
PhosphoSite-
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| TrEMBL |
E5RHI0
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| UniProt Splice Variant |
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| Entrez Gene |
5295
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| UniGene |
Hs.604502
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| RefSeq |
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| HUGO |
HGNC:8979
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| OMIM |
171833
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| CCDS |
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| HPRD |
01381
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| IMGT |
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| EMBL |
AC016564
AC104120
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| GenPept |
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Version 5.4