InnateDB Protein
|
IDBP-474050.4
|
Last Modified
|
2014-10-13 [Report errors or provide feedback]
|
Gene Symbol
|
OSGEPL1
|
Protein Name
|
O-sialoglycoprotein endopeptidase-like 1
|
Synonyms
|
|
Species
|
Homo sapiens
|
Ensembl Protein
|
ENSP00000428859
|
InnateDB Gene
|
IDBG-77371 (OSGEPL1)
|
Protein Structure
|
|
Function |
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. {ECO:0000255HAMAP-Rule:MF_03179}.
|
Subcellular Localization |
Mitochondrion {ECO:0000255HAMAP- Rule:MF_03179, ECO:0000269PubMed:19694617}.
|
Disease Associations |
|
Tissue Specificity |
Widely expressed, with maximum expression in pituitary gland, prostate, rectum and uterus. {ECO:0000269PubMed:19694617}.
|
Comments |
|
Number of Interactions
|
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
|
Molecular Function |
Accession |
GO Term |
GO:0016747
|
transferase activity, transferring acyl groups other than amino-acyl groups
|
GO:0046872
|
metal ion binding
|
|
Biological Process |
GO:0070526
|
threonylcarbamoyladenosine biosynthetic process
|
|
Cellular Component |
|
PDB ID |
|
InterPro |
IPR000905
Gcp-like domain
IPR017861
Kae1/YgjD family
|
PFAM |
PF00814
|
PRINTS |
PR00789
|
PIRSF |
|
SMART |
|
TIGRFAMs |
|
Modification |
|
SwissProt |
Q9H4B0
|
PhosphoSite |
PhosphoSite-Q9H4B0
|
TrEMBL |
E7EVL7
|
UniProt Splice Variant |
|
Entrez Gene |
64172
|
UniGene |
Hs.645448
|
RefSeq |
|
HUGO |
HGNC:23075
|
OMIM |
|
CCDS |
|
HPRD |
07026
|
IMGT |
|
EMBL |
AC013468
AJ295148
AK055441
BC011904
|
GenPept |
AAH11904
AAY14771
BAB70923
CAC14666
|
|
|