Homo sapiens Protein: SLITRK3
Summary
InnateDB Protein IDBP-474449.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLITRK3
Protein Name SLIT and NTRK-like family, member 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000420091
InnateDB Gene IDBG-63825 (SLITRK3)
Protein Structure
UniProt Annotation
Function Suppresses neurite outgrowth. {ECO:0000250}.
Subcellular Localization Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity Expressed in the occipital lobe of the cerebral cortex of the brain. Expressed at higher levels in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas and primitive neuroectodermal tumors. {ECO:0000269PubMed:14557068}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0007409 axonogenesis
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR000483 Cysteine-rich flanking region, C-terminal
IPR001611 Leucine-rich repeat
IPR003591 Leucine-rich repeat, typical subtype
PFAM PF01463
PF00560
PF13504
PF13855
PRINTS
PIRSF
SMART SM00082
SM00369
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O94933
PhosphoSite PhosphoSite-O94933
TrEMBL C9K0R4
UniProt Splice Variant
Entrez Gene 22865
UniGene Hs.101745
RefSeq XP_005247287
HUGO HGNC:23501
OMIM 609679
CCDS CCDS3197
HPRD 18064
IMGT
EMBL AB020655 AC013458 AK290024 BC114621 CH471052
GenPept AAI14622 BAA74871 BAF82713 EAW78599