InnateDB Protein
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IDBP-474668.4
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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CEP70
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Protein Name
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centrosomal protein 70kDa
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000419743
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InnateDB Gene
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IDBG-58487 (CEP70)
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Protein Structure
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Function |
Plays a role in the organization of both preexisting and nascent microtubules in interphase cells. During mitosis, required for the organization and orientation of the mitotic spindle.
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Subcellular Localization |
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269PubMed:14654843, ECO:0000269PubMed:21795687}. Note=Localized at the center of the radial microtubule array in interphase and at the spindle poles during various stages of mitosis.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 63 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
63
[view]
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Protein-Protein |
63
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
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PFAM |
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q8NHQ1
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PhosphoSite |
PhosphoSite-Q8NHQ1
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TrEMBL |
C9JZ04
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UniProt Splice Variant |
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Entrez Gene |
80321
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UniGene |
Hs.701136
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RefSeq |
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HUGO |
HGNC:29972
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OMIM |
614310
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CCDS |
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HPRD |
16779
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IMGT |
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EMBL |
AC020890
AC022497
AC072045
AF202146
AF289495
AK023098
AK299003
AK301913
BC016050
BC030598
CH471052
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GenPept |
AAG35616
AAG35791
AAH16050
AAH30598
BAB14403
BAH12924
BAH13584
EAW79062
EAW79063
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