Version 5.4
Homo sapiens Protein: KY
Summary
InnateDB Protein IDBP-474970.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KY
Protein Name kyphoscoliosis peptidase
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000421297
InnateDB Gene IDBG-57677 (KY)
Protein Structure
UniProt Annotation
Function Probable cytoskeleton-associated protease required for normal muscle growth. Involved in function, maturation and stabilization of the neuromuscular junction. May act by cleaving muscle-specific proteins such as FLNC (By similarity). {ECO:0000250}.
Subcellular Localization Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008233 peptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005856 cytoskeleton
GO:0030018 Z disc
Protein Structure and Domains
PDB ID
InterPro IPR002931 Transglutaminase-like
PFAM PF01841
PRINTS
PIRSF
SMART SM00460
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q8NBH2
PhosphoSite PhosphoSite-Q8NBH2
TrEMBL
UniProt Splice Variant
Entrez Gene 339855
UniGene Hs.146730
RefSeq XP_005247475
HUGO HGNC:26576
OMIM 605739
CCDS
HPRD 13953
IMGT
EMBL AC016931 AC109912 AK090526 AK126993 AK293840
GenPept BAC03471 BAC86780 BAH11610

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca