Version 5.4
Homo sapiens Protein: CFI
Summary
InnateDB Protein IDBP-475211.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CFI
Protein Name complement factor I
Synonyms AHUS3; ARMD13; C3b-INA; C3BINA; FI; IF; KAF;
Species Homo sapiens
Ensembl Protein ENSP00000422009
InnateDB Gene IDBG-33966 (CFI)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 8 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005044 scavenger receptor activity
Biological Process
GO:0006898 receptor-mediated endocytosis
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR001190 SRCR domain
IPR003884 Factor I / membrane attack complex
IPR017448 SRCR-like domain
PFAM PF00530
PRINTS PR00258
PIRSF
SMART SM00057
SM00202
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D6R9Z8
UniProt Splice Variant
Entrez Gene 3426
UniGene Hs.708284
RefSeq
HUGO HGNC:5394
OMIM 217030
CCDS
HPRD 01955
IMGT
EMBL AC126283
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca