Version 5.4
Homo sapiens Protein: BMPR1B
Summary
InnateDB Protein IDBP-475287.3
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BMPR1B
Protein Name bone morphogenetic protein receptor, type IB
Synonyms ALK-6; ALK6; CDw293;
Species Homo sapiens
Ensembl Protein ENSP00000424693
InnateDB Gene IDBG-30667 (BMPR1B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 132 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 132 [view]
Protein-Protein 132 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004675 transmembrane receptor protein serine/threonine kinase activity
GO:0004702 receptor signaling protein serine/threonine kinase activity
GO:0005024 transforming growth factor beta-activated receptor activity
GO:0005524 ATP binding
Biological Process
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway
GO:0023014 signal transduction by phosphorylation
Cellular Component
GO:0016020 membrane
Protein Structure and Domains
PDB ID
InterPro IPR000472 TGF-beta receptor/activin receptor, type I/II
PFAM PF01064
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL D6RAW8
UniProt Splice Variant
Entrez Gene 658
UniGene Hs.738659
RefSeq
HUGO HGNC:1077
OMIM 603248
CCDS
HPRD 04457
IMGT
EMBL AC004061 AC092609 AC093634 AC105395
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca